- 中文名稱
Poly泛素(Ubiquitin) (K63-linked) 單克隆抗體 (HWA4C4)
- 英文名字
- Polyubiquitin (K63-linked) monoclonal antibody (HWA4C4)
- 供應商
- Viva Bioscience
- 產品貨號
- VB2888-100
- 產品報價
- ￥4375/100ug
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Modification of proteins by addition of K63-linked polyubiquitin chains is implicated in a variety of cellular events, including DNA repair, signal transduction and receptor endocytosis.
A monoclonal antibody (mAb) has been generated that specifically recognizes K63-linked polyubiquitin chains, but not any other isopeptide-linked (K6, K11, K27, K29, K33, or K48) polyubiquitin chain or monoubiquitin. The specificity of this K63-linked ubiquitinspecific monoclonal antibody was demonstrated using di-ubiquitin chains and with endogenously ubiquitinylated species in both cell lysates and intact cells.
The antibody has been extensively characterised by ELISA, one-dimensional Western blotting, immunofluorescence utilising cells transfected with wild type and [K63R]ubiquitin, and immunohistochemistry using material derived from the brains of humans suffering from a variety of neurodegenerative disease.
- 應用類型
- 免疫原
- Synthetic peptide containing the ubiquitin K63-isopeptide motif
- 來源宿主
- С
- 反應性
- 保存建議
- 其他
- ?
- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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