Ubiquitin modification of cellular proteins has been shown to be involved with a wide range of biochemical processes including proteasomal degradation, signal transduction, DNA repair, endocytosis and autophagy.
FK1 is a widely used and cited ubiquitin monoclonal antibody that detects polyubiquitinated proteins and ubiquitin chains but does not detect monoubiquitinated proteins nor free ubiquitin.
