Inhibitor of a wide range of protein kinases, including various PKC isoforms, CAM kinase III and most potently PRAK and MAPKAP-K2 (IC50 values of 1.9 and 5 uM respectively). Also shown to act as a direct mitochondrial uncoupler and as a Ca2+ sensitive K+ ion channel activator. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways.
