Proteasomes function in the degradation of unusable or damaged cellular proteins. Proteasome complexes are therefore localized in the nucleus and cytoplasm of eukaryotic cells. The most commonly found proteasome in mammalian cytosol is the 26S proteasome, which is made up of one 20S proteasome core subunit and two 19S subunits. The 20S core particle is in itself made up of two A subunits and two B subunits, which represent the catalytic component. Proteins destined for degradation are first labeled by polyubiquitination before they enter the proteasome core and are broken down.
應用類型
WB | ICC/IF | IP
免疫原
人紅細胞提取的20S proteasome.
來源宿主
兔
反應性
人 | 小鼠
保存建議
廠家推薦藍冰運輸。收到產品后建議保存于-20oC。
其他
StressMarq Biosciences Inc. 在2007年成立于加拿大維多利亞，是一家生物科技公司，專門從事試劑與試劑盒研究，服務范圍遍及3943多個國家。 StressMarq公司的核心技術領域為細胞應激（尤其是熱休克蛋白（HSP）領域，領先全球），離子通道，載體研究，同時在神經科學領域推出特有的具有生物活性的Tau蛋白與A-突觸核蛋白。產品領域涉及到：細胞凋亡、細胞信號、通路和轉運、細胞器標志物、熱休克、神經生物學、神經科學、氧化應激、磷酸化運輸等。除了提供用于進一步研究的相關工具外，Str
