SpyRho 555 is a fluorogenic dye ligand for the RNA aptamer RhoBAST. It is a rhodamine dye that is cell permeable, highly fluorogenic and photostable. With its high affinity and fast on/off binding kinetics to its cognate aptamer RhoBAST, it overcomes many issues associated with live cell RNA imaging. SpyRho 555 is highly suited for widefield, confocal, STED or single molecule localization microscopy in a PAINT like setup. SpyRho 555 enables multicolor imaging with SPY505, SPY595, SPY650, SPY700, SiR and GFP. SpyRho 555 can be imaged with standard TMR or Cy3 settings. Probe quantity allows 100 staining experiments.
