中文名稱

重組人干擾素-λ1(rHu IFN-λ1）

英文名字

Recombinant Human Interferon-λ1 (rHu IFN-λ1)

供應商

Bioworld

產品貨號

PR1050

產品報價

￥詢價/5ug

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

IL-28A, IL-28B, and IL-29, also named interferon-λ2 (IFN-λ2), IFN-λ3, and IFN-λ1, respectively, are newly identified class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11-13% aa sequence identity) and the type I IFN family (15-19% aa sequence identity). The expression of IL-28A, B, and IL-29 is induced by virus infection or double-stranded RNA. All three cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The three proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor β (IL-10 Rβ) and a novel IL-28 receptor α (IL-28 Rα, also known as IFN-λR1). Ligand binding to the receptor complex induces Jak kinase activation and STAT1 and STAT2 tyrosine phosphorylation.

序列

PTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST

來源宿主

Escherichia coli.

溶解建議

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20?C. Further dilutions should be made in appropriate buffered solutions.

保存建議

This lyophilized preparation is stable at 2-8?C, but should be kept at -20?C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8?C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20?C to -70?C. Avoid repeated freeze/thaw cycles.

其他

Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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