- 中文名稱
ACHE 一抗
- 英文名字
- ACHE Primary antibody
- 供應商
- Promab
- 產品貨號
- PMB-32394
- 產品報價
- ¥詢價/100ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. AChE activity may constitute a sensitive biomarker of RBC ageing in vivo, and thus, may be of aid in understanding the effects of transfusion.
- 應用類型
- WB,IHC,FCM
- 免疫原
- Purified recombinant fragment of human ACHE expressed in E. Coli.
- 來源宿主
- Mouse
- 反應性
- Human, Mouse, Monkey, Rat
- 保存建議
- 4℃短期保存;-20℃長期保存。避免凍融循環。
- 其他
- ProMab 生物技術公司通過整合生物信息學、分子生物學、蛋白質表達、純化技術、基因克隆、微生物學和免疫學,利用新型高通量技術開發重組蛋白、抗體和工程細胞系并將其商業化。專注于免疫治療領域,特別是 CAR-T/NK 細胞技術。ProMab 還開發了一種新型的 mRNA 脂質納米顆粒(mRNA-LNP)平臺,用于即用型試劑和定制研究服務,以推進現有產品并擴展到更多的研究領域。

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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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