- 中文名稱
ALPL 一抗
- 英文名字
- ALPL Primary antibody
- 供應商
- Promab
- 產品貨號
- PMB-30337
- 產品報價
- ¥詢價/100ul

- 產品說明書
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- 購買方式
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- 產品新聞

- 背景資料
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
- 應用類型
- WB,IHC,FCM
- 免疫原
- Purified recombinant fragment of human ALPL expressed in E. Coli.
- 來源宿主
- Mouse
- 反應性
- Human
- 保存建議
- 4℃短期保存;-20℃長期保存。避免凍融循環。
- 其他
- ProMab 生物技術公司通過整合生物信息學、分子生物學、蛋白質表達、純化技術、基因克隆、微生物學和免疫學,利用新型高通量技術開發重組蛋白、抗體和工程細胞系并將其商業化。專注于免疫治療領域,特別是 CAR-T/NK 細胞技術。ProMab 還開發了一種新型的 mRNA 脂質納米顆粒(mRNA-LNP)平臺,用于即用型試劑和定制研究服務,以推進現有產品并擴展到更多的研究領域。

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