- 中文名稱
PAX6 一抗
- 英文名字
- PAX6 Primary antibody
- 供應商
- Promab
- 產品貨號
- PMB-30066
- 產品報價
- ¥詢價/100ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells .PAX6 is the most researched of the PAX genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
- 應用類型
- FCM
- 免疫原
- Purified recombinant fragment of human PAX6 expressed in E. Coli.
- 來源宿主
- Mouse
- 反應性
- Human
- 保存建議
- 4℃短期保存;-20℃長期保存。避免凍融循環。
- 其他
- ProMab 生物技術公司通過整合生物信息學、分子生物學、蛋白質表達、純化技術、基因克隆、微生物學和免疫學,利用新型高通量技術開發重組蛋白、抗體和工程細胞系并將其商業化。專注于免疫治療領域,特別是 CAR-T/NK 細胞技術。ProMab 還開發了一種新型的 mRNA 脂質納米顆粒(mRNA-LNP)平臺,用于即用型試劑和定制研究服務,以推進現有產品并擴展到更多的研究領域。

- 注意
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