FAK is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene， but the full-length natures of only two of them have been determined.
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來源宿主
Sf9昆蟲細胞中重組表達
溶解建議
提供的人粘著斑激酶（FAK1）產品為溶液形式；其中人粘著斑激酶（FAK1）產品溶解于50mM Tris pH 7.5，150mM NaCl，0.5mM EDTA，0.02% Triton X-100，2mM DTT，50%甘油溶液中.
