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中文名稱

Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)

英文名字
Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)
供應商
USBiological
產品貨號
P9099-05
產品報價
¥1/1Kit
產品說明書
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背景資料
USBiological品牌是全球有名的抗原抗體和生化試劑供應商,生產世界上種類最多的抗體,用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。武漢艾美捷科技作為USBiological品牌中國區域總代理,是行業中少有的致力于服務客戶,幫助客戶,且擁有獨立的專業銷售團隊、技術支持團隊、市場營銷團隊、進出口報關團隊的高科技生物企業??梢詾槟峁┘皶r的咨詢響應,專業的產品和解決方案支持,穩健快捷的交貨周期,優質放心的售后服務。我們致力于為您提供有價值的產品和服務,在意您的成功!
產品描述
The United States Biological Proteinase-3, Human, BioAssay ELISA Kit is intended for the detection and semi-quantitative determination of antibodies to PR-3 in human serum. The assay is to be used to detect antibodies in a single serum specimen. Proteinase-3 is a lysosomal enzyme that can be found in human neutrophils. There are two subsets of autoantibodies to sample neutrophils, c- ANCA and p-ANCA. The first subtype, c-ANCA, shows cytoplasmic staining by IFA and is diagnostic for Wegener's granulomatosis. The major antigen responsible for the c-ANCA staining is Proteinase-3. The second subtype, p- ANCA, shows perinuclear staining by IFA. The major antigen responsible for the p-ANCA response has been shown to be myeloperoxidase. The ANCA staining patterns are obtained using ethanol-fixed sample neutrophils. Anti- PR-3 autoantibodies have been associated with Wegener's granulomatosis but less often with microscopic polyangiitis. Other antigen specificity's (CAP 57) can be responsible for the c-ANCA pattern. These antigens are generally not diagnostic for PR-3 associated vaculitus diseases. Kit Components:Each kit contains the following components in sufficient quantities to perform the number of tests indicated on the package label.1. Microtiter Plate: 1x96 wells2. Sample Diluent: 1x30ml3. Positive Control, High: 1x400ul4. Calibrator: 1x400ul5. Negative Control: 1x400ul6. Positive Control, Low: 1x400ul7. IgG, IgA, IgM (HRP) Goat x human: 1x15ml8. Wash Buffer, 20X: 1x50ml9. Tetramethylbenzidine (TMB): 1x15ml10. Stop Solution: 1x15ml Storage and Stability:Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
產品特點
針對Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)該產品的特點優勢,歡迎查閱官網提供的產品說明書。
保存建議
建議收到Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)產品后將其置于4°C保存。
其他
Usbiological公司是美國著名的抗體和生化試劑供應商,生產世界上種類最多的抗體,用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。Usbiological公司現已擁有超過50,19234種抗體、抗原和生化產品,為科研用戶提供了諸多超值選擇。
注意
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