- 中文名稱
為建立檢測小鼠血清和細胞培養上清液中IL-10的夾心ELISA試劑盒。
- 英文名字
- For the development of sandwich ELISA kit to measure mouse IL-10 in cell culture supernatants and serum.
- 供應商
- Nordic BioSite
- 產品貨號
- NDC-KBB-FXPJWT-5
- 產品報價
- ¥詢價/5plates

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- 產品新聞

- 背景資料
- Interleukin-10, also called cytokine synthesis inhibitory factor, is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production. IL-10 is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system. IL-10 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. IL-10 significantly affects chemokine biology, because human IL-10 inhibits chemokine production and is a specific chemotactic factor for CD8+ T cells. It suppresses the ability of CD4+ T cells, but not CD8+ T cells, to migrate in response to IL-8. Interleukin-10 gene polymorphisms and interleukin-10 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation.1 The interleukin-10 locus contributes to the heritability of psoriasis susceptibility. With regard to sudden infant death, IL-10 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease The mIL-10 gene is mapped to mouse chromosome 1 and the hIL-10 gene is also mapped to human chromosome 1. The standard product used in this kit is recombinant human IL-10, consisting of 160 amino acids with the molecular mass of 18.6KDa.
- 產品描述
- 白細胞介素-10,也稱為細胞因子合成抑制因子,與腫瘤發生有關,并且已經顯示其基因啟動子多態性與不同的產生量相關。IL-10是一種重要的細胞因子,具有抗炎、抗免疫、抗纖維化等作用。它也是一種重要的調節性細胞因子,其參與延伸到人類免疫系統的不同區域。IL-10是最近描述的一種天然內源性免疫抑制細胞因子,已在人、鼠和其它生物體中鑒定。IL-10顯著影響趨化因子生物學,因為人IL-10抑制趨化因子產生,并且是CD8 + T細胞的特異性趨化因子。它抑制CD4 + T細胞,但不抑制CD8 + T細胞響應IL-8遷移的能力。白細胞介素-10基因多態性和白細胞介素-10產生能力可能與腎移植后皮膚鱗狀細胞癌的發生有關。1白細胞介素-10基因座與銀屑病易感性的遺傳性有關。關于嬰兒猝死,IL-10是特別感興趣的。這是一種免疫調節細胞因子,在感染性疾病的發展中起重要作用。mIL-10基因定位于小鼠1號染色體,hIL-10基因也定位于人1號染色體。本試劑盒使用的標準品為重組人IL-10,由160個氨基酸組成,分子量為18.6KDa。
- 產品特點
- ES(雌激素)ELISA試劑盒
- 保存建議
- -20°C
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領域的高質量和創新產品。 Nordic BioSite 被公認為整個北歐生物醫學研究和診斷產品領域的領導者。他們擁有超過570萬種的產品組合,代理了遍布歐洲和美國的頂級生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長的自產產品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產產品線(共26W+產品)。Nordic BioSite的產品類型主要是抗體,蛋白和試劑盒,產品適用范圍涵蓋15個不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學研究解決方案~
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