- 中文名稱
用于開發夾心ELISA試劑盒,以測定細胞培養上清液、血清和血漿(肝素、EDTA、檸檬酸鹽)中的人IL-6。
- 英文名字
- For the development of sandwich ELISA kit to measure human IL-6 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
- 供應商
- Nordic BioSite
- 產品貨號
- NDC-KBB-CZ88J6-5
- 產品報價
- ¥詢價/5plates

- 產品說明書
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- 購買方式
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- 產品新聞

- 背景資料
- The human interferon-beta 2 gene(IFNB2) product is identical to that for the B-cell stimulation factor-2(BSF-2), the hybridoma growth factor(HGF)("interleukin-6"), and the hepatocyte stimulating factor(HSF). Proteins derived from this gene mediate the plasma protein response to tissue injury(acute-phase response) and regulate the growth and differentiation of both B and T cells. Interleukin-6(IL6) has come to be regarded as a potential osteoporotic factor because it has stimulatory effects on cells of the osteoclast lineage, and, thus, may play a role in the pathogenesis of bone loss associated with estrogen deficiency. IL-6 has many roles essential to the regulation of the immune response, hematopoiesis, and bone resorption. It is involved not only in the hepatic acute phase response but also in adipose tissue metabolism, lipoprotein lipase activity, and hepatic triglyceride secretion. Overproduction of IL-6, a proinflammatory cytokine, is associated with a spectrum of age-related conditions including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes, certain cancers, periodontal disease, frailty, and functional decline. BSF-2 is a novel interleukin consisting of 184 amino acids. The standard product used in this kit is recombinant human IL-6, consisting of 184 amino acids with the molecular mass of 20.3kDa.
- 產品描述
- 人干擾素-β 2基因(IFNB2)產物與B細胞刺激因子-2(BSF-2)、雜交瘤生長因子(HGF)("白細胞介素-6")和肝細胞刺激因子(HSF)的產物相同。來源于該基因的蛋白質介導對組織損傷的血漿蛋白應答(急性期應答)并調節B和T細胞的生長和分化。白細胞介素-6(IL6)被認為是一種潛在的骨質疏松因子,因為它對破骨細胞譜系的細胞具有刺激作用,并因此可能在與雌激素缺乏相關的骨丟失的發病機理中起作用。IL-6對免疫應答、造血和骨吸收的調節具有許多重要作用。它不僅參與肝臟急性期反應,還參與脂肪組織代謝、脂蛋白脂酶活性和肝臟甘油三酯分泌。IL-6(一種促炎細胞因子)的過度產生與一系列年齡相關疾病相關,包括心血管疾病、骨質疏松癥、關節炎、2型糖尿病、某些癌癥、牙周病、虛弱和功能下降。BSF-2是一種由184個氨基酸組成的新型白細胞介素。本試劑盒使用的標準品為重組人IL-6,由184個氨基酸組成,分子量為20.3kDa。
- 產品特點
- 用于開發夾心ELISA試劑盒,以測定細胞培養上清液、血清和血漿(肝素、EDTA、檸檬酸鹽)中的人IL-3
- 保存建議
- -20°C
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領域的高質量和創新產品。 Nordic BioSite 被公認為整個北歐生物醫學研究和診斷產品領域的領導者。他們擁有超過570萬種的產品組合,代理了遍布歐洲和美國的頂級生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長的自產產品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產產品線(共26W+產品)。Nordic BioSite的產品類型主要是抗體,蛋白和試劑盒,產品適用范圍涵蓋15個不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學研究解決方案~
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