- 中文名稱
Rabbit IgG polyclonal antibody for DUSP3 detection. Tested with WB, ICC/IF, FCM, Direct ELISA in Human;Mouse;Rat.
- 英文名字
- Rabbit IgG polyclonal antibody for DUSP3 detection. Tested with WB, ICC/IF, FCM, Direct ELISA in Human;Mouse;Rat.
- 供應商
- Nordic BioSite
- 產品貨號
- NDC-ABB-8QF7TW-100
- 產品報價
- ¥詢價/100ug

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene. It is mapped to 17q21.31. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
- 應用類型
- ELISA,FC,ICC,IF,WB
- 免疫原
- E.coli-derived human DUSP3 recombinant protein (Position: S4-P185).
- 來源宿主
- rabbit
- 反應性
- human,mouse,rat
- 保存建議
- -20
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領域的高質量和創新產品。 Nordic BioSite 被公認為整個北歐生物醫學研究和診斷產品領域的領導者。他們擁有超過570萬種的產品組合,代理了遍布歐洲和美國的頂級生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長的自產產品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產產品線(共26W+產品)。Nordic BioSite的產品類型主要是抗體,蛋白和試劑盒,產品適用范圍涵蓋15個不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學研究解決方案~

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