中文名稱

CD138重組蛋白

英文名字

CD138 Recombinant Protein

供應商

Bioworld

產品貨號

NCP0264

產品報價

￥詢價/500ug

產品說明書

點擊查看

購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

Syndecans are a family of type 1 transmembrane heparan sulphate proteoglycans comprising four members in mammals (SDC-1 to -4) encoded by four syndecan genes. Syndecans are involved in embryonic development, tumorigenesis, and angiogenesis. The extracellular domain harbors attachment sites for heparan sulfate and chondroitin sulfate chains, facilitating interaction with an array of proteins including a plethora of growth factors. In addition, the hydrophobic C-terminal intracellular domain can interact with proteins containing a PDZ domain. These interactions place syndecans as important integrators of membrane signaling. Syndecans undergo proteolytic cleavage causing the release of their extracellular domain (shedding), converting the membrane-bound proteins into soluble molecular effectors. Syndecan 1 (SDC1) is a specific marker for plasmacytic differentiation in hematologic disorders. This cell surface proteoglycan is also expressed in normal epithelial cells and tissues as well as various types of cancer tissues. The extracellular shed form of syndecan 1 remains soluble or accumulates in the extracellular matrix where it binds growth factors, cytokines and other extracellular matrix proteins. This binding activates signaling of bound growth factors or cytokines, which results in enhanced tumor growth, dissemination, angiogenesis, and osteolysis. As a result, the level of syndecan1 protein and its shed form may serve as prognostic factors for a list of malignancies.

序列

因CD138重組蛋白/CD138 Recombinant Protein產品的序列過長，詳情查看產品說明書

來源宿主

E.coli

溶解建議

PBS, 4M Urea, PH7.4

保存建議

Store at 4

其他

Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

分享到：