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中文名稱

Integrin α3 (CD49c)重組蛋白

英文名字
Integrin α3 (CD49c) Recombinant Protein
供應商
Bioworld
產品貨號
NCP0243
產品報價
¥詢價/500ug
產品說明書
點擊查看
購買方式
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產品新聞
背景資料
Integrins are heterodimers composed of non-covalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals
transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. The Integrin α3 chain, also known as very late (activation) antigen 3 (VLA-3), very common antigen 2 (VCA-2), extracellular matrix receptor 1 (ECMR1) and galactoprotein b3 (GAPB3), undergoes posttranslational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with β1 to form an integrin that interacts with many extracellular-matrix proteins.
序列
因Integrin α3 (CD49c)重組蛋白/Integrin α3 (CD49c) Recombinant Protein產品的序列過長,詳情查看產品說明書
來源宿主
E.coli
溶解建議
PBS, 4M Urea, PH7.4
保存建議
Store at 4
其他
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注意
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