- 中文名稱
DDX21 monoclonal antibody
- 英文名字
- DDX21 monoclonal antibody
- 供應商
- Bioworld
- 產品貨號
- MB10822
- 產品報價
- ￥詢價/50ul
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase (Pol) I and II: promotes ribosomal RNA (rRNA) processing and transcription from polymerase II (Pol II) (PubMed:25470060). Binds various RNAs, such as rRNAs, snoRNAs, 7SK and, at lower extent, mRNAs (PubMed:25470060). In the nucleolus, localizes to rDNA locus, where it directly binds rRNAs and snoRNAs, and promotes rRNA transcription, processing and modification. Required for rRNA 2'-O-methylation, possibly by promoting the recruitment of late-acting snoRNAs SNORD56 and SNORD58 with pre-ribosomal complexes (PubMed:25470060, PubMed:25477391). In the nucleoplasm, binds 7SK RNA and is recruited to the promoters of Pol II-transcribed genes: acts by facilitating the release of P-TEFb from inhibitory 7SK snRNP in a manner that is dependent on its helicase activity, thereby promoting transcription of its target genes (PubMed:25470060). Functions as cofactor for JUN-activated transcription: required for phosphorylation of JUN at 'Ser-77' (PubMed:11823437, PubMed:25260534). Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase) (PubMed:9461305). Involved in rRNA processing (PubMed:14559904, PubMed:18180292). May bind to specific miRNA hairpins (PubMed:28431233).
- 應用類型
- WB,ICC/IF
- 免疫原
- A synthetic peptide of human DDX21
- 來源宿主
- Rabbit
- 反應性
- Human
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利
- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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