1,6-果糖雙磷酸酶活性測定試劑盒（比色）-Fructose-1,6-Bisphosphatase Activity Assay Kit (Colorimetric)代理/參數/廠家-細胞分析試劑盒-艾美捷科技有限公司

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產品描述: Fructose-1,6-Bisphosphatase (FBP) (EC 3.1.3.11) is a rate-limiting enzyme for gluconeogenesis. It hydrolyzes Fructose-1,6-Bisphosphate releasing inorganic phosphate and Fructose-6-Phosphate that is further used in the synthesis of glucose. In humans, Fructose-1,6-Bisphosphatase can be found in the form of two isozymes: FBP1 and FBP2. FBP1 is mainly expressed in liver and kidneys, while FBP2 is expressed in all tissues. Deficiency of Fructose-1,6-Bisphoshatase causes hypoglycemia, metabolic acidosis, and unexpected death in infants. Recent studies have found elevated FBP levels subjects dealing with obesity and diabetes. Furthermore, inhibition of FBP increases glucose utilization and insulin sensitivity. Therefore, FBP could serve as a potential target for treating type II diabetes (insulin resistance). BioVision’s FBP activity assay kit provides a quick, reliable test that allows the measurement of FBP enzymatic activity in various samples. In this Assay, FBP hydrolyzes Fructose-1,6-Bisphosphate into Fructose-6-Phosphate (F6P). F6P is used in an enzyme-coupled reaction which reduces a chromophore forming a product with a stable signal that can measured at OD = 450 nm. The assay is simple, sensitive and can detect lower than 100 μU of FBP in variety of samples.

產品特點: Sensitive, specific assay, Validated with animal and cell culture lysates, Includes FBP positive control, Measures FBP enzymatic activity in biological assays

其他: BioVision的公司總部在美麗的舊金山灣地區，它是全球生命科學公司的領導者.BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產品及服務質量.