PicoProbeTM谷氨酰胺酶（GLS）活性測定試劑盒（熒光）-PicoProbeTM Glutaminase (GLS) Activity Assay Kit (Fluorometric)代理/參數/廠家-細胞分析試劑盒-艾美捷科技有限公司

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產品描述: Glutaminase (EC 3.5.1.2) is a mitochondrial enzyme that hydrolyzes glutamine producing glutamate and ammonia. GLS is one of the two key enzymes that are responsible for glutamine homeostasis, the other being glutamine synthetase. Since glutamine is a major metabolic substrate involved in gluconeogenesis, its homeostasis is tightly controlled. Glutaminase has tissue-specific roles in multiple organs, with the isoform GLS1 being expressed in kidneys and brain, and GLS2 being expressed in the liver. It is involved in maintenance of acid-base homeostasis by producing ammonia during renal acidosis in kidneys; and regulation of glutamate –which acts as a neurotransmitter- in the brain. On the other hand, GLS 2 regulates the generation of ammonia in liver by producing urea. Research shows GLS increased activity in individuals facing starvation, diabetes and high protein diets. BioVision’s PicoProbeTM Glutaminase Activity Assay Kit is a simple plate-based fluorometric assay for measuring glutaminase activity in biological samples. GLS hydrolyzes glutamine forming glutamate and ammonia. Glutamate, in the presence of a developer and enzyme mix converts a non-fluorescent probe to a fluorescent product via an enzymatic reaction. The assay can detect as low as 2 μU of glutaminase in biological samples.

產品特點: Validated with relevant biological samples, Includes human GLS as positive control, Sensitive, specific assay for detection of glutaminase activity in biological samples

其他: BioVision的公司總部在美麗的舊金山灣地區，它是全球生命科學公司的領導者.BioVision在開發和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產品及服務質量.