12 G5特異性結合表達重組CXCR 4的人和非人細胞。12 G5抑制一些HIV-2分離株的CD 4非依賴性感染，并且用12 G5預孵育細胞消除合胞體形成。HIV-2/vcp感染的細胞顯示12 G5結合的顯著和選擇性降低。12 G5還抑制HIV-1和HIV-2株誘導CXCR 4 + RD/CD 4細胞的細胞間融合。 原液抗人CXCR4（12G5）抗體該產品同種型對照：Mouse IgG2a In Vivo Isotype Control – Low Endotoxin (C1.18.4) [ICH2245] 緩沖液：ICH3001-100ml，nICH3002-100ml，nICH3003-100ml， 濃度：≥ 2.0 mg/ml 純度：>95% by SDS-PAGE 內毒素：<1.0 EU/mg as determined by the LAL method 制劑：Sterile, preservative-free, solution in PBS. BSA and Azide free.
應用類型
Blocking, Flow Cytometry, Immunocytochemistry, Immunofluorescence Microscopy, Immunohistochemistry, Neutralization, Western Blotting
免疫原
12G5 was produced by immunizing Balb/c mice with CP-MAC-infected Sup-T1 cells. Hybridomas were generated and screened for the ability to inhibit CP-MAC-induced syncytium induction on Sup-T1 cells.
