TCRβ抗體（克隆H57-597）識別αβ胸腺細胞和T淋巴細胞以及自然殺傷T（NKT）細胞上表達的T細胞受體（TCRβ）的β鏈。TCRβ是一種跨膜蛋白，由氨基末端可變區、恒定區和通過二硫鍵與TCR α鏈（TCRα）共價連接的莖段組成。TCRα/β不含信號傳導結構域，而是與TCR信號傳導所必需的CD 3復合物（TCR-CD 3）非共價結合。TCRα/β識別與主要組織相容性復合體（MHC）分子結合的抗原，導致CD 3 ITAM磷酸化和隨后的T細胞活化、增殖和存活。 抗小鼠TCR β（H57-597）抗體體內抗體-超低內毒素該產品同種型對照：Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL) 緩沖液：ICH3001-100ml，nICH3002-100ml，nICH3003-100ml， 濃度：≥ 5.0 mg/ml 純度：>98% by SDS-PAGE and HPLC 內毒素：≤ 0.5 EU/mg as determined by the LAL method 制劑：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
