CD 152,也稱為CTLA-4或Ly-56,在氨基酸序列、結構和基因組組織方面與CD 28具有顯著的相似性。此外,CD 152和CD 28共享共同的B7家族反受體。與CD 28不同,CD 152的表達似乎僅限于活化的T細胞和CD 25 + CD 4+調節性T(Treg)細胞。CD 152被認為在免疫耐受的誘導和維持以及保護性免疫和胸腺細胞調節的發展中起作用。 抗小鼠CTLA-4(UC 10 - 4F 10 -11)體內抗體-低內毒素該產品同種型對照:Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251) 緩沖液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 濃度:≥ 2.0 mg/ml 純度:>95% by SDS-PAGE and HPLC 內毒素:≤ 1.0 EU/mg as determined by the LAL method 制劑:0.01 M phosphate buffered saline (PBS) pH 7.4, without BSA or sodium azide added.
應用類型
Flow Cytometry, Western Blot, Functional Assays, Immunoprecipitation
免疫原
Purified Recombinant Mouse CTLA4 Fc Fusion Protein