Plasmid p-mHMG1 contains the genomic mouse HMGB1 with its own promoter and enhancer, exons and introns (Falciola et al. High mobility group 1 protein is not stably associated with the chromosomes of somatic cells. J Cell Biol 1997, 137: 19-26).Mouse HMGB1 contains only 2 conservative substitutions with respect to human HMGB1.nWhen transfected in mammalian cells, this plasmid increases transiently the HMGB1 content 4- to 7-fold.
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HMGBiotech是一家由HMGB領域的領先科學家Marco E. Bianchi創立的生物技術公司。nHMGBiotech是HMGB51質量控制氧化還原變體的唯一生產商。該公司為活躍在這一有前途的領域的其他研究人員和公司提供試劑、服務和想法，并幫助Bianchi實驗室（the Bianchi lab）開發檢測和試劑。
