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中文名稱

Growth Hormone, Human (hGH) BioAssay ELISA Kit

英文名字
Growth Hormone, Human (hGH) BioAssay ELISA Kit
供應商
USBiological
產品貨號
G9000-01
產品報價
¥1/96Tests
產品說明書
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背景資料
USBiological品牌是全球有名的抗原抗體和生化試劑供應商,生產世界上種類最多的抗體,用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。武漢艾美捷科技作為USBiological品牌中國區域總代理,是行業中少有的致力于服務客戶,幫助客戶,且擁有獨立的專業銷售團隊、技術支持團隊、市場營銷團隊、進出口報關團隊的高科技生物企業??梢詾槟峁┘皶r的咨詢響應,專業的產品和解決方案支持,穩健快捷的交貨周期,優質放心的售后服務。我們致力于為您提供有價值的產品和服務,在意您的成功!
產品描述
Human growth hormone (GH) is a 22kD monomeric protein produced and stored in somatotrophs in the anterior pituitary gland. GH is released from the pituitary into the bloodstream in a pulsatile manner under the regulatory control of hypothalamic somatostatin (SS) and GH-releasing factor (GHRF). The timing and frequency of GH release appears to be regulated by somatostatin, while the amplitude of GH release is determined by GHRF. A minor fraction (~10%) of GH in circulation exists in a smaller 20kD form. GH has profound effects on tissue growth and metabolism, which is thought to be mediated through GH-dependent production of IGF-I and IGF-II, and their associated binding proteins. GH apparently stimulates IGF production after binding to specific cell surface receptors in the liver and, possibly, other tissues. Almost 50% of GH in circulation is bound to a high affinity GH binding protein (GHBP), which represents the extracellular domain of the GH receptor. Deficient GH secretion can occur in a number of clinical conditions. However, evaluation of GH deficiency is complicated by the episodic nature of GH secretion and low circulating levels. A variety of physiologic and pharmacologic stimuli have been used to stimulate pituitary GH release during testing and failure to achieve a normal serum GH level in response to at least 2 GH stimulation or provocative tests is considered to be a diagnostic of GH deficiency. The definition of a normal serum GH response is controversial, although published values generally range from 5-10ng/ml. GH excess (or acromegaly) can be caused either by direct GH hypersecretion or GH excess secondary to GHRF hypersecretion.Kit Components:G9000-01A: Microtiter Plate 1x96wellsG9000-01B: Pab (HRP) 1x12mlG9000-01C: Standard (50ng/ml) 1x1 vialG9000-01D: Standard (25ng/ml) 1x1 vialG9000-01E: Standard (12ng/ml) 1x1 vialG9000-01F: Standard (6ng/ml) 1x1 vialG9000-01G: Standard (2ng/ml) 1x1 vialG9000-01H: Standard (0ng/ml) 1x1 vialG9000-01J: Sample Diluent 1x7mlG9000-01K: Substrate A 1x10mlG9000-01L: Substrate B 1x10mlG9000-01M: Stop Solution 1x14mlG9000-01N: Wash Buffer (20 X) 1x60mlSensitivity: ~0.5ng/mlStorage and Stability:Store at 4°C. Stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
產品特點
針對Growth Hormone, Human (hGH) BioAssay ELISA Kit該產品的特點優勢,歡迎查閱官網提供的產品說明書。
保存建議
建議收到Growth Hormone, Human (hGH) BioAssay ELISA Kit產品后將其置于4°C保存。
其他
Usbiological公司是美國著名的抗體和生化試劑供應商,生產世界上種類最多的抗體,用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。Usbiological公司現已擁有超過50,19234種抗體、抗原和生化產品,為科研用戶提供了諸多超值選擇。
注意
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