WARS is part of the class I tRNA synthetase family. 2 types of tryptophanyl tRNA synthetase exist, a cytoplasmic form, called WARS, and a mitochondrial form, called WARS2. WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. WARS controls ERK, Akt, and eNOS activation pathways that are related with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
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大腸桿菌中重組表達
溶解建議
提供的人色氨酰-tRNA合成酶(WARS)產品為過濾滅菌的無色溶液;其中1mg/ml人人色氨酰-tRNA合成酶(WARS)產品溶解于20mM Tris pH 8, 1mM DTT, 0.1M NaCl, 1mM DTT,10%甘油溶液中.