二溴丙烷是一種巰基反應性蛋白質交聯劑，當兩個烷基化基團都與蛋白質反應時，會產生熒光產物。二溴丙烷具有390/450 nm的激發/發射光譜。 K. Ue等人（1985）?！坝脽晒饨宦搫┓€定肌球蛋白亞片段1中的初級環。“Proceedings of the National Academy of Sciences 82（6）：1658-1662.2）Konno K. K. Ue等人（2000年）?！霸诩∏虻鞍譙1中放置分子內交聯的后果?！癙roceedings of the National Academy of Sciences 97（4）：1461-1466.3）Chen Z. B。L. Akin等人（2006年）?！癙hospholamban的C-末端殘基與心臟肌漿網的Ca 2+泵的交聯，以探索跨膜結構域內的空間和功能相互作用。“Journal of Biological Chemistry 281（20）：14163-14172.4）Lindzen M. K.- E. Gottschalk等人（2006年）。“FXYD蛋白質和Na+ K+-ATP酶之間的結構相互作用：Δ ±/Δ 2/FXYD亞單位化學計量和交聯?！癑ournal of Biological Chemistry 281（9）：5947- 5955.技術數據表
產品描述
Dibromobimane is a thiol reactive protein cross linking reagent that generates a fluorescent product when both of the alkylating groups have reacted with proteins. Dibromobimane has an excitation/ emission spectra of 390/450 nm.References1) Mornet D. K. Ue et al. (1985). "Stabilization of a primary loop in myosin subfragment 1 with a fluorescent crosslinker." Proceedings of the National Academy of Sciences 82(6): 1658-1662.2) Konno K. K. Ue et al. (2000). "Consequences of placing an intramolecular crosslink in myosin S1." Proceedings of the National Academy of Sciences 97(4): 1461-1466.3) Chen Z. B. L. Akin et al. (2006). "Cross-linking of C-terminal Residues of Phospholamban to the Ca2+ Pump of Cardiac Sarcoplasmic Reticulum to Probe Spatial and Functional Interactions within the Transmembrane Domain." Journal of Biological Chemistry 281(20): 14163-14172.4) Lindzen M. K.-E. Gottschalk et al. (2006). "Structural Interactions between FXYD Proteins and Na+ K+-ATPase: ?±/?2/FXYD SUBUNIT STOICHIOMETRY AND CROSS-LINKING." Journal of Biological Chemistry 281(9): 5947-5955.Technical Data Sheet
