NOG是α-酮戊二酸的類似物，并且已發現是涉及α-酮戊二酸的反應如黃嘌呤羥化酶和α-酮戊二酸雙加氧酶的抑制劑。M. M. Li等人（2007年）。“來自構巢曲霉的Fe II和α-酮戊二酸依賴性黃嘌呤羥化酶的純化和表征。“生物化學46（18）：5293-304.2） P. K. Grzyska等人（2005年）。“CoII、NiII和N-草酰甘氨酸抑制FeII/α-酮戊二酸雙加氧酶TauD的動力學和光譜研究。“Biochem Biophys Res Commun 338（1）：191-7。
產品描述
NOG is an analogue of alpha ketoglutarate and has been found to be an inhibitor of reactions involving alpha ketoglutarate such as xanthine hydroxylase and alpha ketoglutarate dioxygenase.References1) Montero-Moran G. M. M. Li et al. (2007). "Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans." Biochemistry 46(18): 5293-304.2) Kalliri E. P. K. Grzyska et al. (2005). "Kinetic and spectroscopic investigation of CoII NiII and N-oxalylglycine inhibition of the FeII/alpha-ketoglutarate dioxygenase TauD." Biochem Biophys Res Commun 338(1): 191-7.
