Periostin is a disulfide linked 90 kDa，811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment，attachment and spreading. Additionally，periostin expression has previously been shown to be significantly increased by both transforming growth factor beta-1（TGFbeta1） and bone morphogenetic protein （BMP-2）. OSF-2 has a typical signal sequence，followed by a cysteine-rich domain，a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin
Periostin mRNA is expressed in the developing mouse embryonic and fetal heart，and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart.
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來源宿主
大腸桿菌中重組表達
溶解建議
提供的人成骨細胞特異性因子2（Periostin）產品為過濾滅菌的凍干粉末；該凍干粉末是從含0.5 mg/ml人成骨細胞特異性因子2（Periostin）的0.05M醋酸鹽緩沖液（pH 4）中過濾滅菌并凍干產生的.我們建議加0.2 ml 0.1M 醋酸鹽緩沖液（pH 4）使粉末完全溶解.如要使pH值更大，我們建議通過相關緩沖液進一步稀釋到10ug/ml.過高的濃度會影響Periostin的溶解性.
