IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production,and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine,and thus negatively regulate its biological activity.
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來源宿主
大腸桿菌中重組表達
溶解建議
提供的大鼠白介素-18(rIL 18)產品為過濾滅菌的白色凍干粉末;該凍干粉末是從含1mg/ml大鼠白介素-18(rIL 18)的0.4 x PBS pH 7.2溶液中凍干產生的.我們建議加無菌的18MΩ-cm水以配制工作儲存液到100ug/ml,后繼實驗過程中可根據實驗要求進一步稀釋.