IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form,it circulates in the plasma,prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants,encoding different isoforms,have been characterized.
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來源宿主
大腸桿菌中重組表達
溶解建議
提供的人胰島素樣生長因子結合蛋白-3(IGFBP 3)產品為過濾滅菌的白色凍干粉末;該凍干粉末是從含人胰島素樣生長因子結合蛋白-3(IGFBP 3)的20mM Tris HCL溶液中凍干產生的.我們建議加無菌的18MΩ-cm水以配制工作儲存液到100ug/ml,后繼實驗過程中可根據實驗要求進一步稀釋.