CKMT1A is in charge of the transfer of high energy phosphate from mitochondria to the cytosolic carrier， creatine. CKMT1A is a member of the creatine kinase isoenzyme family and exists as two isoenzymes， sarcomeric MtCK and ubiquitous MtCK， encoded by separate genes. Mitochondrial creatine kinase arises in two different oligomeric forms: dimers and octamers， unlike the exclusively dimeric cytosolic creatine kinase isoenzymes. Numerous malignant cancers with poor prognosis have displayed overexpression of ubiquitous mitochondrial creatine kinase which is linked to high energy turnover and inability to remove cancer cells through apoptosis.
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大腸桿菌中重組表達.
溶解建議
提供的重組人線粒體肌酸激酶1A產品形式為無菌的無色溶液.
保存建議
建議將重組人線粒體肌酸激酶1A產品整瓶保存于4℃可保存2-4周. 長期保存，請置于-20℃.長期保存，推薦添加載體蛋白 （0.1% HSA or BSA）.請避免反復凍融.
