Macrophage Inflammatory Proteins （MIP） belong to the family of chemotactic cytokines known as chemokines. In humans， there are two major forms， MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes （neutrophils， eosinophils and basophils） which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1 （IL-1）， IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.
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來源宿主
大腸桿菌中重組表達
溶解建議
提供的重組小鼠巨噬細胞炎癥蛋白-1 alpha（CCL3）， His Tag產品為無菌的澄清溶液形式.
保存建議
整瓶保存于4℃時，應在2-4周用完.長期保存應置于-20℃.
長期保存，推薦添加載體蛋白 （0.1% HSA or BSA）.
請避免反復凍融.
