Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.
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來源宿主
大腸桿菌中重組表達
溶解建議
提供的重組小鼠生長調節致癌基因α(CXCL1), His標簽產品為無菌的無色溶液形式.
保存建議
整瓶保存于4℃時,應在2-4周用完.長期保存應置于-20℃.
長期保存,推薦添加載體蛋白 (0.1% HSA or BSA).
請避免反復凍融.