- 中文名稱
重組NT-4，小鼠
- 英文名字
- RecombinantNT-4,Mouse
- 供應商
- Bioworld
- 產品貨號
- BK0145
- 產品報價
- ￥詢價/10ug
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Neurotrophin-4 (NT-4) is a small secreted cytokine, and belongs to the Neurotrophin (NT) family, which also includes Brain Derived Neurotropic Factor (BDNF), Nerve Growth Factor (NGF), and NT-3. NT family members are all derived from similar sized protein precursors, composed of N-terminal propeptides and C-terminal mature domains, which are separated by posttranslational proteolytic cleavage. NT-4 (along with NT-3) is foundin the brains of mammals . In vivo, NT-4 binds to the common receptor, p75NTR, and a tyrosine kinase receptor, TrkB. The heterotrimeric complex activates the NFκB transcription factor. NT-4 is essential for the differentiation and wiring regulation of the central and peripheral nervous systems during development, and is related to important diseases including Alzheimer’s.Recombinant mouse Neurotrophin-4 (rmNT-4) produced in E.coli is a noncovalently linked homodimer containing two non-glycosylated polypeptide chainsof 131 amino acids. A fully biologically active molecule, rmNT-4 has a molecular mass of 14.0kDaanalyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- MGVSETAPA SRRGELAVCD AVSGWVTDRR TAVDLRGREV EVLGEVPAAG GSPLRQYFFE TRCKAESAGE GGPGVGGGGC RGVDRRHWLS ECKAKQSYVR ALTADSQGRV GWRWIRIDTA CVCTLLSRTG RA
- 來源宿主
- Escherichia coli.
- 溶解建議
- Reconstituted in 50mM acetic acid or ddH2O at 100 μg/mL.
- 保存建議
- Lyophilized recombinant mouse Neurotrophin-4 (rmNT-4) remains stable up to 6 months at -80
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
-
