中文名稱

重組瘦素，大鼠

英文名字

RecombinantLeptin,Rat

供應商

Bioworld

產品貨號

BK0120

產品報價

￥詢價/1mg

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

Leptin is a cytokine belonging to the Interleukin 6 family, and has a four-helix bundle structure. Leptin is encoded by the ob gene, and produced and secreted by white adipose tissue. The receptors of Leptin are Type I cytokine receptors, which exist in two different forms: a short form expressed in multiple tissues, and a long form expressed exclusively in the central nervous system (CNS). Upon binding to Leptin, the receptors activate the JAK/STAT3 pathway and PI3K, and stimulate transcriptional programs that regulate feeding behavior, metabolic rate, endocrine axes, and glucose fluxes. The deficiency of Leptin in human and mouse causes morbid obesity, diabetes, and neuroendocrine anomalies. Leptin also has effects on reproduction and immunity. In summary, Leptin is a pivotal cytokine controlling energy balance, and as such has profound effects on human health. Recombinant rat Leptin (rrLeptin) produced in E.coli is a single non-glycosylated polypeptide chain containing 147 amino acids. A fully biologically active molecule, rrLeptin has a molecular mass of 16.3 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

序列

MVPIHKVQD DTKTLIKTIV TRINDISHTQ SVSARQRVTG LDFIPGLHPI LSLSKMDQTL AVYQQILTSL PSQNVLQIAH DLENLRDLLH LLAFSKSCSL PQTRGLQKPE SLDGVLEASL YSTEVVALSR LQGSLQDILQ QLDLSPEC

來源宿主

Escherichia coli.

溶解建議

Reconstituted in ddH2O at 100 μg/mL.

保存建議

Lyophilized recombinant rat Leptin (rrLeptin) remains stable up to 6 months at -80

其他

Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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