- 中文名稱
硬骨素(SOST)Elisa試劑盒
- 英文名字
- Sclerostin ELISA Kit
- 供應商
- Biomedica Immunoassays
- 產品貨號
- BI-20492
- 產品報價
- ￥12x8tests
- 產品說明書
- 點擊查看
- 購買方式
- 90%產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Sclerostin is a 22.5 kDa secreted glycoprotein that functions as a potent inhibitor of Wnt signaling. It acts by binding to the Wnt-coreceptor LRP5/6 thus inhibiting bone formation by regulating osteoblast function and promoting osteoblast apoptosis. The Sclerostin protein consists of two flexible N- and C-terminal arms and a cystine-knot with three loops, whereas the second loop binds to the LRP5/6 complex. Sclerostin is classically considered to be a monomeric protein, but data from Hernandez and colleagues (Hernandez et al., 2014) postulate that circulating sclerostin has a dimeric configuration. In addition, it is not yet well documented if also Sclerostin fragments circulate, but the comparison of different Sclerostin ELISAs suggest that fragments exist as well (Dallas et al., 2013).
- 產品描述
- Method
Sandwich ELISA, HRP/TMB, 12×8-well detachable strips
Sample type
Serum, EDTA plasma, citrate plasma, hepar?n plasma, urine, cell culture supernatant
Sample volume
20 μl / well
Assay time
18-24 h / 1 h / 30 min
Sensitivity
3.2 pmol/l (= 72 pg/ml)
Standard range
0 – 240 pmol/l (= 0 – 5,400 pg/ml)
Conversion factor
1 pmol/l = 22.5 pg/ml (MW: 22.5 kDa)
Precision
In-between-run (n=6): ≤ 10 % CV
Within-run (n=8): ≤ 7 % CV
Specificity
Endogenous and recombinant human Sclerostin.
Cross-reactivity
The assay does not cross-react with Wise (Sostdc1) or Noggin. The assay does not cross-react with rat or mouse Sclerostin.
- 產品特點
- 保存建議
- +4°C
- 其他
- Biomedica Immunoassay(bmgrp)公司成立于1988年, 總部位于奧地利維也納，主要致力于研究、開發和生產基于ELISA方法用于臨床前研究相關標記物檢測的工具。迄今為止Biomedica Immunoassay公司在心血管檢測及骨代謝檢測領域開發了一系列特色ELISA檢測試劑盒，Biomedica Immunoassay的生產過程符合GMP/GLP指南，并符合ISO 9001:2015管理體系，有CE認證。Biomedica Immunoassay的產品根據FDA， EMEA和ICH指南進行驗證，并具有驗證報告。
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- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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