- 中文名稱
成熟的BDNF / proBDNF組合快速ELISA試劑盒：人，小鼠，大鼠
- 英文名字
- Mature BDNF/proBDNF Combo Rapid ELISA Kit: Human, Mouse, Rat
- 供應商
- Biosensis
- 產品貨號
- BEK-2240
- 產品報價
- ￥已停產
- 產品說明書
- 點擊查看
- 購買方式
- Biosensis中國區現貨中心已經建立，大部分產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. Post Translation Modification (PTM): The propeptide is N-glycosylated and glycosulfated. PTM: Converted into mature BDNF by plasmin (PLG) (By similarity).
- 產品描述
- The addition of a substrate (3,3,5,5-tetramethylbenzidine, TMB) yields a coloured reaction product which is directly proportional to the concentration of mature BDNF or proBDNF present in samples and protein standards. A BDNF and proBDNF positive control (QC sample) is provided to assure consistent assay performance.
Both ELISA kits contain high quality protein calibrators. The Mature BDNF ELISA kit employs a recombinant E.coli-derived human mature BDNF standard approved by the World Health Organization (WHO, www.nibsc.org). The amino acid sequence of mature BDNF is identical for human, mouse, rat and a number of other species. This kit therefore is suitable to measure mature BDNF in all these species and uses the same antibodies and antigen. The proBDNF ELISA kit employs a recombinant mammalian, cleavage-resistant human proBDNF standard produced by Biosensis and validated against externally available proBDNF proteins. Due to a high degree of amino acid sequence homology, mouse and rat proBDNF can be quantified and expressed as human proBDNF equivalents. Internal Biosensis validation suggests that the use of the human standard provided in this kit will provide estimates that are identical, or close, to the actual levels of rat and mouse proBDNF present in rodent samples.
- 產品特點
- 該ELIAS試劑盒包含：2 x 96孔預包被條孔板（可拆卸） (1 x BDNF antibody, 1 x proBDNF antibody), protein standards, QC sample, detection reagents, heterophilic antibody blocker, wash and sample buffers, substrate buffer and detailed protocols.
- 保存建議
- 廠家推薦冰袋運輸。廠家推薦試劑盒保存于4 °C
- 其他
- Biosensis專注于神經科學領域的抗體和試劑的開發，特別是神經營養因子和神經營養因子受體。 近30年來，Biosensis一直是該領域的全球領航者和OEM供應商。除神經營養因子，我們的神經科學產品組合還被廣泛用于神經退行性疾病、神經發育和神經代謝的研究。重點研究領域包括阿爾茨海默氏癥（AD）、帕金森氏癥（PD）和肌萎縮側索硬化（ALS）疾病，以及自噬和代謝應激障礙，包括肥胖、代謝綜合征的研究、神經免疫學和炎癥。Biosensis的產品系列不僅包括持續增長的神經科學研究抗體系列，還包括200多種定量研究ELISAs試劑盒（1板或2板，自由選擇），組織染色（退化神經元染色試劑盒、病理髓鞘染色試劑盒、淀粉樣斑塊染色試劑等）和細胞可視化試劑（染色）以及針對神經科學和細胞疾病研究的純化的蛋白質。我們的抗體和試劑已被廣泛應用于各種技術，包括蛋白質印跡，免疫組織化學，流式分析，共聚焦顯微鏡實時成像，生物抑制和細胞培養以及克隆。
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- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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