- 中文名稱
3'-Azido-2'， 3'-ddTTP
- 英文名字
- 3'-Azido-2',3'-ddTTP
- 供應商
- Baseclick
- 產品貨號
- BCT-28-L
- 產品報價
- ￥詢價/5umol
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- 3'-Azido-2'， 3'-ddTTP(3'-Azido-2',3'-ddTTP)背景資料,請查看該產品的使用說明書
- 產品描述
- Azide modified nucleotide closely resemble natural nucleotides and are the basis of chemoenzymatic mRNA labeling. Due to the small size of the azide group, 3′-Azido-2′,3′-ddTTP is well accepted by T7 RNA polymerase and poly(A) polymerase and terminale deoxynucleotidyl transferase (Tdt) for enzymatic incorporation. This is highly beneficial, as labeling of mRNA with our approach is modular and not limited to enzymatic compatibility of bulky pre-labeled nucleotides. Moreover, only a very limited number of such pre-modified nucleotides, mainly dye-labeled ones, are commercially available. Internal and external studies successfully showed e.g. that the poly(A) polymerase adds specifically and sequence independently single azido terminator to the 3’-end of RNA.The main advantage: Any mRNA can be site-specifically labeled without special requirements or altered production protocols at the 3’-end.
- 產品形式
- Liquid
- 保存建議
- -20°C, 無RNA酶
- 其他
- Baseclick于2008成立于2008年德國慕尼黑，BaseClick的核心競爭力源于其專有的銅催化疊氮-炔環加成（CuAAC）點擊化學技術。該技術由2001年諾貝爾化學獎得主Barry Sharpless教授發明，BaseClick擁有在核酸領域應用該技術的全球獨家許可。相比傳統方法，點擊化學具有反應迅速、條件溫和、產率高、選擇性強等顯著優勢，可實現從小分子寡核苷酸到大基因片段的高效、精準功能化修飾。目前的應用領域包括：核酸標記技術、Edu細胞增殖試驗，PCR標記試劑盒，FISH探針，（高度）修飾的寡核苷酸等等，Baseclick跟Thermo Fisher，Roche，Merck，abcam，BD Bioscience等諸多知名品牌建立了合作關系。
- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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