- 中文名稱
Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay
- 英文名字
- Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay
- 供應商
- USBiological
- 產品貨號
- B0807-02D
- 產品報價
- ￥1/1Kit
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- USBiological品牌是全球有名的抗原抗體和生化試劑供應商，生產世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。武漢艾美捷科技作為USBiological品牌中國區域總代理，是行業中少有的致力于服務客戶，幫助客戶，且擁有獨立的專業銷售團隊、技術支持團隊、市場營銷團隊、進出口報關團隊的高科技生物企業?？梢詾槟峁┘皶r的咨詢響應，專業的產品和解決方案支持，穩健快捷的交貨周期，優質放心的售后服務。我們致力于為您提供有價值的產品和服務，在意您的成功！
- 產品描述
- The Bcl-2 family consists of a number of evolutionarily conserved proteins containing Bcl-2 homology domains (BH) that regulate apoptosis through control of mitochondrial membrane permeability and release of cytochrome c (1-3). Four BH domains have been identified (BH1-4), which mediate protein interactions. The family can be separated into three groups based upon function and sequence homology: pro-surivival members including Bcl-2, Bcl-xL, Mcl-1, A1, and Bcl-w; pro-apoptotic proteins including Bax, Bak, and Bok; and “BH3 only” proteins Bad, Bik, Bid, Puma, Bim, Bmf, Noxa, and Hrk. Interactions between death-promotingand death-suppressing Bcl-2 family members has led to a rheostat model in which the ratio of pro-apoptotic and anti-apoptotic proteins controls cell fate (4). Thus, pro-survival members exert their behavior by binding to and antagonizing death-promoting members. In general, the “BH3-only members” can bind to and antagonize the pro-survival proteins leading toincreased apoptosis (5). While some redundancy of this system likely exists, tissue specificity and transcriptional and post-translational regulation of many of these family members can account for distinct physiological roles. Several phosphorylation sites have been identified withinBcl-2 including Thr56, Ser70, Thr74, and Ser87 (6).Included antibodies:B0807-02D1 Bcl 2, phosphorylated (Ser70) 20ulW, F H 28kDRabbitB0807-02D2 Bcl-2, phosphorylated (Thr56) 20ul W H 28kDRabbitB0807-02D3 Bcl-2 20ul W, IP, IHC H 28kDRabbitB0807-02D4 Bcl-XL20ul W, IP, IHC H, M, R, Mk 30kDRabbitB0807-02D5 Mcl-120ul W H 40kDRabbitB0807-02D6 IgG (HRP)100ul GoatStorage and Stability:May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot. Freeze at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 產品特點
- 針對Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay該產品的特點優勢，歡迎查閱官網提供的產品說明書。
- 保存建議
- 建議收到Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay產品后將其置于-20°C保存。
- 其他
- Usbiological公司是美國著名的抗體和生化試劑供應商，生產世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細胞術等多種檢測方法。Usbiological公司現已擁有超過50,19234種抗體、抗原和生化產品，為科研用戶提供了諸多超值選擇。
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- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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