CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions， cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands， such as osteopontin， collagens， and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation， recirculation and homing， hematopoiesis， and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers.
應用類型
Staining， immunohistochemistry. For staining， use 10μl/1，000，000 cells. Titer for IH should be determined by the investigator.
