Mediator of ErbB2-driven cell motility 1 （MEMO1） is a member of the UPF0103 family. MEMO1 regulates cell migration by transmitting extracellular chemotactic signals to the microtubule cytoskeleton. Furthermore， MEMO1 controls the localization of APC and CLASP2 to the cell membrane， using the regulation of GSK3B activity. MEMO1 is essential for breast carcinoma cell migration， suggesting a key role in tumorigenesis. MEMO1 is also a mediator of ERBB2 signaling.
應用類型
【MEMO1】小鼠抗人細胞運動調節蛋白1Mouse Anti Human Mediator of Cell Motility 1該產品的應用類型查閱產品說明書。
免疫原
Anti-human MEMO1 mAb， is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MEMO1 amino acids 1-297 purified from E. coli.
