催乳素 ELISA-Prolactin ELISA代理/參數/廠家-ELISA試劑盒-艾美捷科技有限公司

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中文名稱: 催乳素 ELISA

英文名字: Prolactin ELISA

供應商: Ansh Labs

產品貨號: AL-199

產品報價: ￥詢價/96wellmicrotiter

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背景資料

Prolactin is a 198-amino acid, 23 kDa polypeptide hormone secreted in significant amounts by the anterior pituitary gland. The prolactin molecule has extensive sequence homology with growth hormone and placental lactogen1. Recent studies have revealed molecular heterogeneity for prolactin in both pituitary extracts and blood2,3. Prolactin secretion is regulated by complex mechanisms involving neurotransmitters and endocrine hormones. Many of the regulatory pathways involve hypothalamic secretion of dopamine, which inhibits prolactin secretion4. Prolactin, in synergy with estrogen, plays an important physiologic role in the initiation and maintenance of mammary land growth and lactation in humans1,4.
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nIn addition, prolactin may have effects on cell growth in other tissues and on immune function. Particularly when present in high concentrations, prolactin may have inhibitory effects on gonadal function. Prolactin is present in several body fluids, including plasma, amniotic fluid, milk, mucosal secretions, and cerebrospinal fluid. Relative elevations in plasma prolactin concentrations occur during ovulation, pregnancy, nursing and stress1,2,4. Abnormal elevations in plasma prolactin levels, or hyperprolactinemia, can occur as a result of pituitary adenomas, and may also be seen in other anatomic and traumatic abnormalities involving the pituitary gland (e.g., tumors, surgery, trauma), as a consequence of certain pharmacologic agents, and primary hypothyroidism. Low prolactin levels, or hypoprolactinemia, is observed in cases of hypopituitarism5,6.
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nReferences:
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Nicoll CS, Mayer GL, Russell SM: Structural features of prolactins and growth hormones that can be related to their biological properties. Endocrin Rev 7:169-203, 1986.

Sinha YN: Structural variants of prolactin: occurrence and physiological significance. Endocrin Rev 16:354-369, 1995.

Liu MY, Zhou S, Tang T: Radioreceptor assay for human prolactin and the heterogeneity of prolactin in the sera from patients with pituitary prolactin-secreting adenoma. Chin J Pathophysiol 10:420, 1994.

Lambert SWJ, MacLeod RM: Regulation of prolactin secretion at the level of the lactotroph. Physiol Rev 70:219-318, 1990.

Liu MY, Zhou S: The new aspects of prolactin action. Prog Physiol Sci 21:36, 1990.s et al: Measurement of serum ferritin by a two-site immunoradiometric assay. Ann Biochem 61:209, 1974.

Burtis CA,Ashwood ER: Tietz Textbook of Clinical Chemistry, 2nd ed. W.B. Saunders Company, Philadelphia, 1994, p 1675.

HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5

DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 - Explosive Azide Hazard. Available: http:// www.cdc.gov/niosh.

Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.

產品描述: Prolactin Enzyme-Linked Immunosorbent Assay (ELISA) Kit provides materials for the quantitative measurement of prolactin in human serum.

產品特點

保存建議: Store at 2 to 8°C until expiration date.

其他: Ansh labs是開發和生產免疫檢測試劑盒和定制生物技術檢測產領創者，總部位于美國休斯敦，公司產品遍及全球80多個國家。公司于2011年成立，核心團隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領域近40年，擁有全球領先的核心技術，以及多年經驗生物技術研發經驗的科學家團隊，產品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領域，圍繞最新的免疫分析技術，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。 Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產品研究和新型免疫檢測技術的先驅者。優勢產品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。