主要胰高血糖素前段片段（MPGF） ELISA-Major Proglucagon Fragment (MPGF) ELISA代理/參數/廠家-ELISA試劑盒-艾美捷科技有限公司

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中文名稱: 主要胰高血糖素前段片段（MPGF） ELISA

英文名字: Major Proglucagon Fragment (MPGF) ELISA

供應商: Ansh Labs

產品貨號: AL-175

產品報價: ￥詢價/96wellmicrotiter

產品說明書: 點擊查看

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產品新聞

背景資料: Major Proglucagon Fragment (MPGF) is an 86-amino acid hormone secreted from the pancreas1-3. MPGF is identified as the Carboxy terminal portion of proglucagon that contains two glucagon-related sequences. The MPGF sequence is highly conserved among mammals. Tissue specific processing of proglucagon in the pancreas releases MPGF. Intestinal processing of MPGF releases the Glucagon-Like Peptides 1 and 2 (GLP-1 and GLP-2)1-5. Measuring the circulating levels of MPGF will help in understanding the defective or abnormal metabolic pathways leading to diabetes and obesity. This kit is designed to measure MPGF.
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nReferences:
n1. Müller et al., (2017) The New Biology and Pharmacology of Glucagon. Physiol Rev 97: 721–766.
n2. Drucker DJ, Habener JF, Holst JJ Discovery, characterization, and clinical development of the glucagon-like peptides (2017) J Clin Invest. 127(12):4217-4227.
n3. Bonic A, Mackin RB (2003) Expression, purification, and PC1-mediated processing of human proglucagon, glicentin, and major proglucagon fragment. Protein Expr Purif 28:15–24.
n4. Amato A, Baldassano and Flavia Mulè. GLP2: an underestimated signal for improving glycaemic control and insulin sensitivity. Journal of Endocrinology (2016) 229, R57–R66
n5. Baldassano S, Amato A, Rappa F, Cappello F & Mulè F (2016b) Influence of endogenous glucagon like peptide-2 on lipid disorders in mice fed a high fat diet. Endocrine Research.
nVol. 41, Iss. 4.
n6. HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
n7. DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 - Explosive Azide Hazard. Available: http://www.cdc.gov/niosh.
n8. Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.

產品描述: The Major Proglucagon Fragment (MPGF) enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of MPGF in EDTA plasma and other biological fluids.

產品特點

保存建議: Store at 2 to 8°C until expiration date.

其他: Ansh labs是開發和生產免疫檢測試劑盒和定制生物技術檢測產領創者，總部位于美國休斯敦，公司產品遍及全球80多個國家。公司于2011年成立，核心團隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領域近40年，擁有全球領先的核心技術，以及多年經驗生物技術研發經驗的科學家團隊，產品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領域，圍繞最新的免疫分析技術，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。 Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產品研究和新型免疫檢測技術的先驅者。優勢產品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。