- 中文名稱
胰高血糖素 ELISA
- 英文名字
- Glucagon ELISA
- 供應商
- Ansh Labs
- 產品貨號
- AL-157
- 產品報價
- ¥詢價/96wellmicrotiter

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Glucagon and Oxyntomodulin, a peptide hormone secreted by the alpha cells of pancreas, share identical amino acid sequence in the N-terminal 29 aa. Glucagon is a 29-amino acid polypeptide processed from proglucagon in pancreatic alpha cells.1 In intestinal L-cells proglucagon is cleaved into glicentin, corresponding to proglucagon residues no 1-69. Glicentin can further be processed into oxyntomodulin, corresponding to proglucagon residues no 33-69. These peptides are released simultaneously upon stimulation.
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nGlucagon has shown to have an effect opposite to that of insulin, i.e. it raises blood glucose levels. It causes the liver to convert glycogen into glucose, which is then released into the blood stream.2-4 During hypoglycaemia, glucagon secretion offers a protective feedback mechanism, defending the organism against damaging effects of glucose deficiency in the brain and nerves.5
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nReferences:
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n - Sandoval DA and D’Alessio DA. Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease. Physiol Rev 95:513-548.
n - Bagger JI et al (2011) Glucagon antagonism as a potential therapeutic target in type 2 diabetes. Diabetes, Obesity and Metabolism 13:965-971.
n - Holst J et al (2004) Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab 287: E199-206.
n - Holst J (2010) Glucagon and Glucagon-Like Peptides 1 and 2. Results Probl Cell Differ 50:121-135.
n - Young A (2005) Inhibition of Glucagon Secretion. Advances in Pharmacology 52:151-171.
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- 產品描述
- The Glucagon ELISA kit measures Glucagon with no detectable cross-reactivity to Glicentin, Oxyntomodulin, GLP-1, GLP-2, or GRPP. Simple procedure, 2.5 hour incubations, no extraction needed, no special collection tube required. Relevant dynamic range and sensitivity.
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- 產品特點
- 保存建議
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是開發和生產免疫檢測試劑盒和定制生物技術檢測產領創者,總部位于美國休斯敦,公司產品遍及全球80多個國家。公司于2011年成立,核心團隊來自于Diagnostic system laboratory,專注于女性健康和激素檢測領域近40年,擁有全球領先的核心技術, 以及多年經驗生物技術研發經驗的科學家團隊,產品覆蓋生殖健康,高危妊娠,腫瘤,糖尿病等多個疾病領域,圍繞最新的免疫分析技術,多種蛋白和單克隆抗體,如AMH,BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產品,也同時涵蓋小鼠,大鼠,狗,羊,牛等靈長類多個物種的獨特的物種特異性的試劑。
Ansh labs 坐落于美國德克薩斯州,是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司,也是最早專注激素類產品研究和新型免疫檢測技術的先驅者。優勢產品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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