- 中文名稱
MenoCheck picoAMH ELISA
- 英文名字
- MenoCheck picoAMH ELISA
- 供應商
- Ansh Labs
- 產品貨號
- AL-124
- 產品報價
- ￥詢價/96wellmicrotiter
- 產品說明書
- 點擊查看
- 購買方式
- 90%產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Menopause is the cessation of menstrual cycling and fertility. Clinically it is recognized by a cessation of menstrual bleeding; menopause is a woman’s status after her final menstrual period (FMP). Menstrual cycling and bleeding are driven by the dynamics of ovarian follicle maturation. Because a woman is born with a limited number of follicles (non-growing “primodial” follicles) that cannot be replaced and are slowly consumed by the monthly maturation of smaller groups of follicles (primary, secondary and antral growing follicles), the natural cause of menopause is the absence of follicles. However, many natural (e.g., certain diseases, starvation, etc.) or interventional processes (chemotherapy, surgical removal of the uterus, ovaries, or pituitary gland, etc.) can cause a cessation of menses that can be either irreversible (e.g., functionally the same as menopause) or reversible. Diagnosing menopause (e.g. the FMP) currently is only done unequivocally after cessation of menses for 12 months in a previously cycling woman.
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nNaturally occurring (i.e., as a result of aging) menopause is referred to as “spontaneous” and, on average, occurs at the age of 51 years, but there is a very large variance of approximately +/- 10 years with respect to the occurrence of menopause in healthy women. Ovarian function deteriorates gradually leading up to menopause and contributes to the variance observed among women with respect to menopausal status. Ovarian function affects, primarily via the steroid hormones produced by growing follicles, virtually every organ in a woman’s body. Physiological responses to the gradual or abrupt loss of ovarian function include a multitude of menopausal “symptoms” and consequences that affect a woman’s health and quality of life. 1,2
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nDuring several years leading up to the FMP and several years immediately following the FMP is a time called the climacteric or menopausal transition, when a woman transitions from the reproductive to a non-reproductive state. The transition is highly variable among women with respect to duration and intensity of associated physiological changes, which affect her well being and level of disease risk. Thus, determining where a woman is in this process must be individualized and is clinically important, particularly during the menopausal transition and the 12 months following the FMP. Quantitative measurement of blood levels of Anti-Müllerian Hormone using the picoAMH assay can aid in determining a woman’s menopausal status during the menopausal transition.
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nBlood levels of AMH represent one of the markers available to clinicians to determine where a woman is in her menopausal transition. Other clinical tests relevant in this context are estradiol which is produced only by follicles in their final stages of maturation, and thus only indirectly reflects the total number of follicles in the ovary, and FSH which reflects the negative feedback by estradiol on pituitary gland secretion (i.e., also an indirect marker of ovarian follicular pool based on large follicle function). In contrast AMH is produced by the majority of ovarian follicles (primary, secondary and antral).
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nBlood levels of AMH have been shown to be highly correlated with the number of primordial follicles in an ovary (i.e., true ovarian reserve).3 The picoAMH assay was developed to allow more sensitive measurements. AMH measured using the picoAMH assay provides a significant new parameter to aid physicians in determining the status of women during the menopausal transition.
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nREFERENCES
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n1. Stuenkel CA, Davis SR, Gompel A, Lumsden MA, Murad MH, Pinkerton JV, Santen RJ 2015 Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 100:3975-4011
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n2. Su HI, Freeman EW 2009 Hormone changes associated with the menopausal transition. Minerva Ginecol 61:483-489
- 產品描述
- The?MenoCheck? picoAMH ELISA is FDA cleared for in vitro diagnostic use as an aid in the determination of menopausal status in women between 42 and 62 years of age.?This is the only AMH test with the sensitivity to quantify declining AMH concentrations in women who are entering their menopausal transition.
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nResearch Use Only and CE versions are available.
- 產品特點
- 保存建議
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是開發和生產免疫檢測試劑盒和定制生物技術檢測產領創者，總部位于美國休斯敦，公司產品遍及全球80多個國家。公司于2011年成立，核心團隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領域近40年，擁有全球領先的核心技術， 以及多年經驗生物技術研發經驗的科學家團隊，產品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領域，圍繞最新的免疫分析技術，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。
Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產品研究和新型免疫檢測技術的先驅者。優勢產品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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