- 中文名稱
picoIL-6 ELISA
- 英文名字
- picoIL-6 ELISA
- 供應商
- Ansh Labs
- 產品貨號
- AL-1007-r
- 產品報價
- ￥詢價/96wellmicrotiter
- 產品說明書
- 點擊查看
- 購買方式
- 90%產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Interleukin-6 (IL-6) is a member of the IL-6 superfamily, which consists of polypeptide cytokines with a four-α-helix structure and a molecular mass of 21 to 28 kDa. It is produced by the lymphoid and non-lymphoid cells with pleotropic functions ranging from hematopoiesis and metabolic regulation to inflammation, autoimmunity, and acute phase response.
nUnder normal conditions, IL-6 plays an important role in cellular homeostasis. However, during inflammatory conditions, the concentration of IL-6 increases in several folds. This relates its clinical relevance as a major alarm signal in humans in response to infections (sepsis/septicemia), inflammation, autoimmunity, and cancer.1-3 Increased concentrations of IL-6 have been reported in localized (prosthetic joint infections, periodontitis), and systemic (eg, sepsis, coronavirus 2019 [COVID-19]) infections, autoimmune conditions (eg, rheumatoid arthritis (RA), systemic lupus erythematosus, ankylosing spondylitis, and inflammatory bowel disease), and cancers. 3-7 Overall, IL-6 cytokine is nonspecific biomarker of systemic inflammation that may have relevance in clinical decision making in the appropriate context.
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nReferences:
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n1. Rose-John S: Interleukin-6 signalling in health and disease. F1000Res. 2020 Aug 20;9: F1000 Faculty Rev-1013.
n2. Jones SA, Jenkins BJ: Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer. Nat Rev Immunol. 2018; 18:773-89
n3. Rose-John S, Winthrop K, Calabrese L: The role of IL-6 in host defence against infections: immunobiology and clinical implications. Nat Rev Rheumatol. 2017 Jul;13(7):399-409
n4. Gallo J, Svoboda M, Zapletalova J, et al: Serum IL-6 in combination with synovial IL-6/CRP shows excellent diagnostic power to detect hip and knee prosthetic joint infection. PLoS One. 2018;13: e0199226
n5. Song J, Park DW, Moon S, et al: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions. BMC Infect Dis. 2019; 19:968
n6. Galvan-Roman JM, Rodriguez-Garcia SC, Roy-Vallejo, E, et al: IL-6 serum levels predict severity and response to tocilizumab in COVID-19: An observational study. J Allergy Clin Immunol. 2021; 147:72-80
n7. Udomsinprasert W, Jittikoon J, Sangroongruangsri S, et al: Circulating levels of interleukin-6 and interleukin-10, but not tumor necrosis factor-alpha, as potential biomarkers of severity and mortality for COVID-19: Systematic review with meta-analysis. J Clin Immunol. 2021; 41:11-22
- 產品描述
- The picoIL-6 enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of IL-6 in serum and other biological fluids.
- 產品特點
- 保存建議
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是開發和生產免疫檢測試劑盒和定制生物技術檢測產領創者，總部位于美國休斯敦，公司產品遍及全球80多個國家。公司于2011年成立，核心團隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領域近40年，擁有全球領先的核心技術， 以及多年經驗生物技術研發經驗的科學家團隊，產品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領域，圍繞最新的免疫分析技術，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。
Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產品研究和新型免疫檢測技術的先驅者。優勢產品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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