- 中文名稱
CD42c 多克隆抗體
- 英文名字
- CD42c Polyclonal Antibody
- 供應商
- 艾美捷
- 產品貨號
- ABP58068
- 產品報價
- ￥替代產品
- 產品說明書
- 點擊查看
- 購買方式
- 中國區現貨中心已經建立，90%產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, the authenticity of this product has been questioned. Yet another less abundant GPIb beta mRNA species of 3.5 kb, expressed in nonhematopoietic tissues such as endothelium, brain and heart, was shown to result from inefficient usage of a non-consensus polyA signal in the neighboring upstream gene (SEPT5, septin 5). In the absence of polyadenylation from its own imperfect site, the SEPT5 gene produces read-through transcripts that use the consensus polyA signal of GP1BB.
- 應用類型
- IHC-p、ELISA
- 免疫原
- 合成多肽：來源于人員源 CD42c 蛋白，氨基酸序列為：90-150
- 來源宿主
- 兔
- 反應性
- 人、小鼠、大鼠
- 保存建議
- 自發貨之日起，-20°C可穩定保存1年。為最大限度的避免損失，請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。
- 其他
- 艾美捷科技與國內外優秀的生物試劑供應商優保持著密切的合作關系，目前已成為眾多國際知名品牌的中國總代理或一級代理，主要包括：AmyJet、AATBioquest、Abbexa、Abnova、Agrisera、Anogen、Atlas Antibodies、Biosensis、Biovision、BioVendor、CaissonLabs、Cell?Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、HycultBiotech、ImmunoReagents、ImmunoStep、Jackson、LifeSensors、LigaTrap、Lumiprobe、Mabtech、Matreya、NorgenBiotek、Origene、ProImmune、ProSpec、ScyTek、SolisBioDyne、SouthernBiotech、StressMarq、SySy、USBiological、TRC等，可以在短時間內為用戶提供專業的前沿資訊、完備的產品及物流服務。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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