- 中文名稱
Methyl Arachidonyl Fluorophosphonate (50 mg)
- 英文名字
- MAFP, Methyl Arachidonyl Fluorophosphonate, 5Z,8Z,11Z,14Z-eicosatetraenyl-phosphonofluoridic acid, methyl ester
- 供應商
- Cayman
- 產品貨號
- 70660-50
- 產品報價
- ￥10290/50 mg
- 產品說明書
- 點擊查看
- 購買方式
- 產品新聞
- 背景資料
- Methyl arachidonyl fluorophosphonate (MAFP) is a selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2. It inhibits A23187-induced arachidonic acid release from human platelets with an IC50 value of 0.6 uM. The IC50 value for inhibition of iPLA2 from P388D1 cells is 0.5 uM. MAFP is a potent inhibitor of fatty acid amide hydrolase, exhibiting an IC50 value of 2.5 nM. MAFP also binds to the CB1 receptor in rat brain membrane preparations. The IC50 values for MAFP and arachidonyl ethanolamide in this assay are 20 and 40 nM, respectively.
- 產品描述
- A selective, active-site directed, irreversible inhibitor of cPLA2 and iPLA2; inhibits A23187-induced arachidonic acid release from human platelets (IC50 = 0.6 uM) and iPLA2 release from P388D1 cells (IC50 = 0.5 uM); a potent inhibitor of FAAH (IC50 = 2.5 nM); binds to the CB1 receptor in rat brain membrane preparations(IC50 = 20 nM)
- 產品形式
- 保存建議
- -80
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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