Apolipoproteins are a family of fatty-acid binding proteins that transport fat through the bloodstream in the form of lipoproteins. ApoF （apolipoprotein F），also known as LTIP （lipid transfer inhibitor protein），is a 308 amino acid secreted protein that belongs to the apolipoprotein family. Expressed in liver tissues and also existing in plasma，ApoF inhibits the activity of CETP （cholesteryl ester transfer protein） and，via this inhibition，functions to regulate cholesterol transport. The gene encoding ApoF maps to human chromosome 12，which encodes over 1，100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions，including hypochondrogenesis，achondrogenesis，Kniest dysplasia，Noonan syndrome and Trisomy 12p，which causes facial developmental defects and seizure disorders.
應用類型
Western blot: ~1:1000， IHC: ~1:10-1:50.
免疫原
This APOF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human APOF.
