MDC （macrophage-derived chemokine） is a 69-amino acid CC chemokine with a N-terminal sequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages. Recombinant MDC attracts monocyte-derived dendritic cells，activated lymphocytes and natural killer cells. MDC has anti-HIV-1 activity. Expression of MDC mRNA in macrophages is enhanced by LPS，IL-1B and TNF. MDC is a functional ligand for CCR4.
應用類型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Rat spleen tissue lysate can be used as a positive control.
免疫原
E. coli-expressed mouse MDC
來源宿主
兔
反應性
經檢測驗證，可與小鼠、大鼠種屬來源的MDC蛋白發生免疫反應.
保存建議
提供的MDC抗體產品為100 ug 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）緩沖液中.請將該MDC抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.
